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慢性阻塞性肺疾病患者CAT评分与心功能相关性研究

发表时间:2017-06-15  浏览量:106  下载量:12
全部作者: 赵欣,涂友慧,戴梦缘,季爽,费广鹤
作者单位: 合肥市第二人民医院呼吸内科;安徽医科大学第一附属医院呼吸内科
摘 要: 目的:探讨慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患者的COPD评估测试(COPD assessment test,CAT)评分与心功能参数间的相关性。方法:对2016年6月至12月就诊于安徽医科大学第一附属医院呼吸内科的138例COPD患者进行前瞻性研究,符合入组条件的患者98例,其中轻-中度组48例、重-极重度组50例,同期40例健康体检者为对照组。采用彩色多普勒超声测定并记录肺动脉压(pulmonary artery pressure,PAP)和心功能参数[右心房面积(RA-V)、右室前后径(RVD)、右心室游离壁厚度(RVFW)、左心房横径(LAD)、左心室内径(LVD)、三尖瓣瓣环收缩期位移(TAPSE)、射血分数(LVEF)、每搏输出量(SV)、心肌做功指数(Tei指数)],所有受试者均完成CAT评分量表、肺功能参数、动脉血气测定。结果:COPD患者CAT评分与PAP均具有显著正相关性(P<0.01);CAT评分与右心结构功能参数(RA-V、RVD、RVFW)呈正相关;CAT评分与右心效能参数Tei呈显著正相关,而与TAPSE呈显著负相关,P均<0.05;CAT评分与左心结构功能参数(LAD、LVD)及左心效能参数(LVEF、SV)无明显相关性,P均>0.05. 结论:COPD患者CAT评分与右心功能参数存在显著相关性,与左心功能参数无明显相关性,提示CAT可用于COPD右心功能严重程度的评估,从而拓宽了CAT的临床应用范围。
关 键 词: 内科学;慢性阻塞性肺疾病;CAT;心功能
Title: Correlation of CAT score and heart function in chronic obstructive pulmonary disease patients
Author: ZHAO Xin, TU Youhui, DAI Mengyuan, JI Shuang, FEI Guanghe
Organization: Pulmonary Department, Hefei Second People’s Hospital; Pulmonary Department, The First Affiliated Hospital of Anhui Medical University
Abstract: Objective: To investigate the correlation of chronic obstructive pulmonary disease (COPD) assessment test (CAT) score and the heart function in COPD patients. Methods: 138 patients diagnosed COPD were prospectively studied. Finally, 98 matches were recruited, including 48 mild-to-moderate COPD patients, 50 severe-to-very severe COPD patients, and 40 health subjects as normal control. Pulmonary artery pressure (PAP), the heart function parameters (RA-V, RVD, RVFW, LAD, LVD, TAPSE, LVEF, SV, Tei) were measured and recorded by color Doppler ultrasound. Pulmonary function, arterial blood gas were evaluated for each subject. Meanwhile, all subjects completed the CAT questionnaire independently. Results: Positive correlations were found between CAT scores and PAP (P<0.01), CAT and the parameters of right ventricular function (RA-V, RVFW, RVD, Tei), while negative correlation was found between CAT and TAPSE (P<0.05). No correlation was found between the CAT scores and the parameters of left ventricular function (LAD, LVD, LVEF, SV) (P>0.05). Conclusion: The CAT scores of COPD patients were found significantly correlated with the parameters of right ventricular function, but not correlated with the parameters of left ventricular function, which indicates that CAT may also be used as a useful instrument to evaluate the severity of right heart function in COPD patients, so that can broaden the clinical application scope of the CAT.
Key words: internal medicine; chronic obstructive pulmonary disease; CAT; heart function
发表期数: 2017年6月第11期
引用格式: 赵欣,涂友慧,戴梦缘,等. 慢性阻塞性肺疾病患者CAT评分与心功能相关性研究[J]. 中国科技论文在线精品论文,2017,10(11):1203-1209.
 
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