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抗肿瘤纳米药物的传递障碍及改进策略

发表时间:2017-06-15  浏览量:80  下载量:10
全部作者: 王群,何仲贵,赵东阳
作者单位: 沈阳药科大学无涯学院
摘 要: 总结了抗肿瘤纳米药物传递过程的影响因素,例如肿瘤血管的异常,纳米药物的粒径、形状、表面电荷等,并提出相应的改进策略。通过对肿瘤血管的修复及纳米药物自身性质的改善,能够促进纳米药物向肿瘤部位的传递,以此来更好地发挥其抗肿瘤作用。
关 键 词: 药剂学;抗肿瘤纳米药物;综述;传递障碍;改进策略
Title: Delivery of anticancer nanomedicines: transport barriers and improvement strategies
Author: WANG Qun, HE Zhonggui, ZHAO Dongyang
Organization: School of Wuya, Shenyang Pharmaceutical University
Abstract: This paper summarizes the factors which can influnence delivery process of anticancer nanomedicines, for example the abnormal angiogenesis, the size, shape and surface charge of nanomedicines. Then, the paper puts forward corresponding improvement strategies. It can promote the delivery of nanomedicines to tumor areas and then exert the anti-tumor effect by means of restoring angiogenesis and improving the properties of nanomedicines.
Key words: pharmaceutics; anticancer nanomedicines; review; transport barriers; improvement strategies
发表期数: 2017年6月第11期
引用格式: 王群,何仲贵,赵东阳. 抗肿瘤纳米药物的传递障碍及改进策略[J]. 中国科技论文在线精品论文,2017,10(11):1223-1230.
 
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