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五肽重复蛋白的结构和功能研究进展

发表时间:2024-03-29  浏览量:188  下载量:25
全部作者: 李锟,朱荣利,龙凤
作者单位: 武汉大学药学院
摘 要: 五肽重复蛋白(pentapeptide repeat proteins,PRPs)是一类超家族蛋白,在近3 500个物种中有超过38 000个序列,大多数属于蓝藻,但在生命的所有分支中都有分布,PRPs在不同物种中功能各异,在生物体内涉及到多个生物学过程。本文主要对PRPs的五肽重复序列、三维结构以及相关功能的特点进行总结,旨在阐述PRPs的蛋白结构特征以及在不同物种中相关的生理功能,为后续PRPs的深入研究提供重要的理论依据。
关 键 词: 微生物学;五肽重复蛋白;综述;晶体结构;生物学功能
Title: Advances in the structural and functional study of pentapeptide repeat proteins
Author: LI Kun, ZHU Rongli, LONG Feng
Organization: School of Pharmaceutical Sciences, Wuhan University
Abstract: The pentapeptide repeat proteins (PRPs) are a large superfamily with over 38 000 sequences in nearly 3 500 species, mostly belonging to cyanobacteria but distributed in all branches of life. PRPs have different functions in different species and are involved in several biological processes in living organisms. In this paper, we mainly summarize the characteristics of PRPs, three-dimensional structures and related functions of PRPs, aiming to elucidate the protein structures and related physiological functions of PRPs in different organisms and provide an important theoretical basis for the subsequent in-depth study of PRPs.
Key words: microbiology; pentapeptide repeat protein; review; crystal structure; biological function
发表期数: 2024年3月第1期
引用格式: 李锟,朱荣利,龙凤. 五肽重复蛋白的结构和功能研究进展[J]. 中国科技论文在线精品论文,2024,17(1):1-9.
 
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