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人类Y染色体P4回文序列的对称性分析
发表时间:2010-04-15 浏览量:1619 下载量:836
全部作者: | 李茂亿,胡哲娇,蒋虎,吴晶,邱文元 |
作者单位: | 兰州大学化学化工学院,功能有机分子化学国家重点实验室 |
摘 要: | 通过DNA序列比对的方法,对人类Y染色体上P4回文序列中存在的对称性破缺规律进行初步研究。分析结果表明:P4回文序列的突变容易发生在结构相似的碱基之间;破缺,特别是插入和缺失容易发生在简单重复序列区。这些对称性破缺规律将有助于更深入地研究P4和Y染色体上其他回文序列的起源及进化过程。 |
关 键 词: | 生物数学;对称性破缺;序列比对;人类 Y染色体;P4回文结构;重复序列 |
Title: | The symmetry analysis of palindrome P4 in the human Y chromosome |
Author: | LI Maoyi, HU Zhejiao, JIANG Hu, WU Jing, QIU Wenyuan |
Organization: | The symmetry analysis of palindrome P4 in the human Y chromosome |
Abstract: | In this paper, sequence alignment methods have been used to reveal some symmetry breaking characters of palindrome P4 in the human Y chromosome. The results show that mutations between nucleotides are more likely to occur within purines or pyridines; and insertions and deletions may prefer in simple repeat area. These results make a novel approach to characterize DNA sequence, which provide helpful basis for further studies on the origins and evolutions of P4 and Y chromosome. |
Key words: | biomathematics; symmetry breaking; sequence alignment; human Y chromosome; palindrome P4; repeat sequence |
发表期数: | 2010年4月第7期 |
引用格式: | 李茂亿,胡哲娇,蒋虎,等. 人类Y染色体P4回文序列的对称性分析[J]. 中国科技论文在线精品论文,2010,3(7):682-685. |
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