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1 010例唇腭裂患者的临床资料分析
发表时间：2010-06-15 浏览量：1716 下载量：790
| 全部作者： | 马红霞，赵望泓，张荣强，展秀荣，黄业翔 |
| 作者单位： | 兰州大学口腔医学院；兰州大学公共卫生学院；甘肃省第二人民医院口腔科 |
| 摘 要： | 目的：了解先天性唇腭裂患病的状况与特点，分析与唇腭裂发生有关的影响因素，为唇腭裂病因探讨及预防提供依据。方法：对2000年1月至2009年3月住院的1 010例先天性唇腭裂患者进行回顾性统计分析。结果：本组病例中，单纯唇裂为222例（21.98%），唇裂伴腭裂为620例（61.39%），单纯腭裂为168例（16.63%）；总体男性多于女性（1.89∶1），但在不完全腭裂中，女性多于男性（1∶0.77）；单侧唇裂伴或不伴腭裂及完全腭裂中，左侧多于右侧（1.71∶1）；有遗传史的病例数为64例，占总例数的6.34%；唇腭裂患者母亲妊娠前3个月接触风险因素者有356例（35.25%）。结论：唇腭裂的病因复杂，婚前遗传病的检测和孕期保护是目前降低唇腭裂发生率的重要措施。 |
| 关 键 词： | 口腔医学；唇裂；腭裂；病因 |
| Title： | Statistical analysis of 1 010 patients with cleft lip and palate |
| Author： | MA Hongxia, ZHAO Wanghong, ZHANG Rongqiang, ZHAN Xiurong, HUANG Yexiang |
| Organization： | School of Stomatology, Lanzhou University；School of Public Health, Lanzhou University；Department of Stomatology, Second People's Hospital of Gansu Province |
| Abstract： | Objective: To know the clinical and deformity condition in patients with cleft lip and palate (CLP), analyze certain specific factors related with CLP, as well as furnish evidence for etiology and prevention to CLP. Methods: 1 010 patients in hospital from January, 2000 to March, 2009 were surveyed and their clinic data were analyzed statistically. Results: There were cleft lip 222 cases (21.98%), cleft lip with cleft palate 620 cases (61.39%), and cleft palate 168 cases (16.38%). Males were more than females (1.89∶1) in all cases, but in uncompleted cleft palate, females were more than males (1∶0.77). The left side was more than the right side (1.71∶1) in cases of the unilateral cleft lip with or without palate and the completed palate. 64 cases (6.34%) had definitive genetic factor. Mother underwent danger factors in the first three months of pregnancy: 356 cases (35.25%) were found in all cases. Conclusion: The cause of the cleft lip and palate is complicated. At present, detection of genetic disease before marriage and pregnancy protection is an important measure to reduce the incidence of cleft lip and palate. |
| Key words： | stomatology; cleft lip; cleft palate; etiology |
| 发表期数： | 2010年6月第11期 |
| 引用格式： | 马红霞，赵望泓，张荣强，等. 1 010例唇腭裂患者的临床资料分析[J]. 中国科技论文在线精品论文，2010，3（11）：1137-1140. |
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