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减轻体重对PCOS患者血清脂联素水平的影响
发表时间：2018-09-14 浏览量：1371 下载量：166
| 全部作者： | 陈亚肖，狄娜，黄佳，杨冬梓 |
| 作者单位： | 中山大学孙逸仙纪念医院妇产科 |
| 摘 要： | 目的：探讨减轻体重对多囊卵巢综合征（polycystic ovary syndrome，PCOS）患者血清脂联素水平的影响。方法：纳入PCOS患者150例，检测并对比所有患者体重改变前后的血清脂联素水平，分析患者血清脂联素水平变化与体重改变的关系。结果：按照体重指数（body mass index，BMI）将患者分为3组，结果显示脂联素水平在BMI 18.7～19.9 kg/m2组和BMI 24.0～25.8 kg/m2组间有统计学差异[(9.7±2.8) μg/L vs. (7.3±2.7) μg/L，P<0.05]。按照患者的减重幅度将以上患者分为3组，结果显示减重1.6～2.9 kg组和减重3.0～4.7 kg组患者减重前后的血清脂联素水平有统计学差异（P<0.05）。结论：PCOS患者的血清脂联素水平与BMI呈负相关，减轻体重可以增加患者的脂联素水平。 |
| 关 键 词： | 妇产科学；多囊卵巢综合征；脂联素；体重指数 |
| Title： | Effect of weight loss on serum adiponectin level in patients with polycystic ovary syndrome |
| Author： | CHEN Yaxiao, DI Na, HUANG Jia, YANG Dongzi |
| Organization： | Department of Obstetrics and Gynecology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University |
| Abstract： | Objective: To study the effect of weight loss on serum adiponectin level in patients with polycystic ovary syndrome (PCOS). Methods: The study involved 150 patients with PCOS. All patients were detected in serum adiponectin level before and after their weight loss, and the comparison was made to evaluate the change of serum adiponectin level associated with weight loss. Results: All patients were divided into three groups according to their body mass index (BMI). The results showed that there were significant differences in adiponectin levels between BMI 18.7-19.9 kg/m2 group and BMI 24.0-25.8 kg/m2 group [(9.7±2.8) μg/L vs. (7.3±2.7) μg/L, P<0.05]. The patients were divided into three groups according to their weight loss. The results showed that the serum adiponectin levels before and after weight loss were significantly different (P<0.05) in patients who lost weight 1.6-2.9 kg and 3.0-4.7 kg. Conclusion: Serum adiponectin level was negatively correlated with BMI in PCOS patients and weight loss could increase their serum adiponectin level. |
| Key words： | obstetrics and gynecology; polycystic ovary syndrome; adiponectin; body mass index |
| 发表期数： | 2018年9月第17期 |
| 引用格式： | 陈亚肖，狄娜，黄佳，等. 减轻体重对PCOS患者血清脂联素水平的影响[J]. 中国科技论文在线精品论文，2018，11（17）：1705-1707. |
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