您的位置:首页  > 论文页面

海洋真菌Aspergillus aculeatus次级代谢产物的研究

发表时间:2009-06-15  浏览量:1539  下载量:603
全部作者: 王宇,李占林,刘涛,田黎,华会明
作者单位: 沈阳药科大学中药学院;国家海洋局第一海洋研究所;青岛科技大学化工学院
摘 要: 为从海洋微生物次级代谢产物中寻找新的抗肿瘤活性代谢产物,为开发新型抗肿瘤药物提供先导化合物,从采自南海潮间带红树植物小花老鼠
关 键 词: 药物化学;海洋真菌;棘孢曲霉;次级代谢产物
Title: 海洋真菌Aspergillus aculeatus次级代谢产物的研究
Author: WANG Yu, LI Zhanlin, LIU Tao, TIAN Li, HUA Huiming
Organization: School of Traditional Chinese Medicine, Shenyang Pharmaceutical University;The First Institute of Oceanography, State Oceanic Administration;College of Chemical Engineering, Qingdao University of Science & Technology
Abstract: In order to search new antitumor metabolites from secondary metabolites of marine microorganisms and provide lead compounds for developing new antitumor medicines, the secondary metabolites of marine fungus Aspergillus aculeatus, which was obtained from mangrove plant Acanthus ebracteatus in the South China Sea, were investigated. Eight compounds were isolated and identified from acetone ultrasonic extract of mycelia and ethyl acetate extract of fermentation broth of the Aspergillus aculeatus. The eight compounds comprised 1,3,5-trihydroxy-7-methylanthraquinone (1); 2-hydroxy-3-(4-hydroxy-phenyl)-propionic acid (2); 3-isopropyl-6-methylpiperazine-2, 5-dione (3); 3-sec-butyl-6-methylpiperazine-2, 5-dione (4); uridine (5); uracil (6); adenine (7); and succinic acid (8).
Key words: medicinal chemistry; marine fungus; Aspergillus aculeatus; secondary metabolite
发表期数: 2009年6月第11期
引用格式: 王宇,李占林,刘涛,等. 海洋真菌Aspergillus aculeatus次级代谢产物的研究[J]. 中国科技论文在线精品论文,2009,2(11):1170-1173.
 
0 评论数 0
暂无评论
友情链接