您的位置:首页  > 论文页面

酶催化拆分及合成重要手性中间体扁桃酸的研究进展

发表时间:2010-10-15  浏览量:1714  下载量:790
全部作者: 张国艳,曹淑桂
作者单位: 吉林大学分子酶学工程教育部重点实验室;吉林大学化学学院
摘 要: 酶催化反应具有反应条件温和、选择性强、副反应少、产率高、产品光学纯度高及无污染等优点,利用酶催化反应制备手性中间体扁桃酸已成为国际上研究的新热点。结合国内外研究,对用生物催化剂酶进行拆分及合成手性中间体扁桃酸的研究现状和发展趋势进行了论述。
关 键 词: 生物化学与分子生物学;手性中间体;综述;扁桃酸;生物催化剂;酶;合成;拆分
Title: Progress in resolution and synthesis of important chiral intermediate mandelic acid by enzyme
Author: ZHANG Guoyan, CAO Shugui
Organization: Key Laboratory for Molecular Enzymology and Engineering, Ministry of Education, Jilin University; College of Chemistry, Jilin University
Abstract: Enzymes are remarkable catalysts with wide substrate specificities, high stereoselectivity, high regioselectivity, mild reaction conditions and low pollution. Recent research has focused on exploring enzyme-catalyzed reaction to produce chiral intermediate mandelic acids. The study on the recent advances and future development of resolution and synthesis of chiral intermediate mandelic acid by enzyme has been discussed here.
Key words: biochemistry and molecular biology; chiral intermediate; reviews; mandelic acid; biocatalyst; enzyme; synthesis; resolution
发表期数: 2010年10月第19期
引用格式: 张国艳,曹淑桂. 酶催化拆分及合成重要手性中间体扁桃酸的研究进展[J]. 中国科技论文在线精品论文,2010,3(19):1955-1960.
 
0 评论数 0
暂无评论
友情链接