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生物大分子链在生物电作用下穿越生物膜的动力学行为研究

发表时间:2014-08-15  浏览量:1579  下载量:589
全部作者: 温晓会
作者单位: 成都理工大学地球物理学院
摘 要: 采用分子动力学(molecular dynamics, MD)模拟方法,研究生物大分子链在生物电作用下穿越生物膜上孔道的动力学行为。模拟发现:生物大分子的链长与穿孔时间之间有很好的标度关系;短链穿孔与长链穿孔的物理机制不同,所以它们各自的穿孔过程也不相同;此外,随着外场力的变化,穿孔时间也是不同的。研究结果有助于对复杂生命过程的了解以及对潜在应用起到理论指导作用。
关 键 词: 凝聚态物理学;生物大分子链;生物电;穿孔时间
Title: A study on the dynamics of a biomacromolecule chain passing through biomembrane under bio-electricity action
Author: WEN Xiaohui
Organization: College of Geophysics, Chengdu University of Technology
Abstract: In this paper, molecular dynamics (MD) method is adopted to study the dynamics of a biomacromolecule chain passing through biomembrane under bio-electricity action. It is found that the length of biomacromolecule chain has well scale relation with the time of passing through biomembrane; due to the difference of physics mechanics between short and long biomacromolecule chain, their translocation process is also different. In addition, with the magnitude change of bio-electricity, the translocation time is different. This study helps us to understand the complex life process and acts as theoretical direction to potential applications.
Key words: condensed matter physics; biomacromolecule chain; bio-electricity; translocation time
发表期数: 2014年8月第15期
引用格式: 温晓会. 生物大分子链在生物电作用下穿越生物膜的动力学行为研究[J]. 中国科技论文在线精品论文,2014,7(15):1551-1555.
 
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