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响应面法优化复序橐吾中多酚提取工艺

发表时间:2015-09-15  浏览量:1484  下载量:417
全部作者: 赵岩,彭蕾,郭世杰,蔡恩博,刘双利,杨鹤,张连学
作者单位: 吉林农业大学中药材学院;吉林大学第一医院新生儿科
摘 要: 目的:研究复序橐吾多酚的最佳提取工艺。方法:以复序橐吾为材料,应用岭回归和响应面分析法,研究乙醇浓度、超声时间、液固比及其交互作用对多酚提取率的影响。结果:复序橐吾中多酚的最佳提取条件为乙醇浓度41.6%(体积比)、液固比228.3 mL/g、提取时间26.7 min. 在此条件下,复序橐吾中多酚提取率达4.48%(质量比). 结论:研究建立的工艺模型适用于复序橐吾多酚的提取,可用于实际生产。
关 键 词: 中药化学;复序橐吾;多酚;提取工艺;响应面分析;岭回归
Title: Optimization of extraction process for polyphenols from Ligularia jaluensis by response surface methodology
Author: ZHAO Yan, PENG Lei, GUO Shijie, CAI Enbo, LIU Shuangli, YANG He, ZHANG Lianxue
Organization: Chinese Medicine Material College, Jilin Agricultural University; Department of Neonatology, The First Hospital of Jilin University
Abstract: Objective: To study the best extraction technique conditions of polyphenols from Ligularia jaluensis. Methods: Using the combination of ridge regression and response surface analysis method, taking L. jaluensis as materials, the interaction effects of the ethanol concentration, ultrasonic time and liquid-solid ratio on total polyphenols extraction yield were studied. Results: The results show that the optimal levels of liquid-to-material ratio, extaction time and ethanol concentration were determined to be 228.3 mL/g, 26.7 min and 41.6% (volume ratio). Under these conditions, the extraction yield of total polyphenols is 4.48% (mass ratio). Conclusion: The research process model is suitable for polyphenols extraction from L. jaluensis, which can be used in practical production.
Key words: pharmaceutical chemistry; Ligularia jaluensis; polyphenol; extraction technique; response surface analysis; ridge regression
发表期数: 2015年9月第17期
引用格式: 赵岩,彭蕾,郭世杰,等. 响应面法优化复序橐吾中多酚提取工艺[J]. 中国科技论文在线精品论文,2015,8(17):1787-1794.
 
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