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疏肝理脾法配合胰岛素治疗2型糖尿病伴高脂血症30例临床疗效观察

发表时间:2015-09-15  浏览量:1898  下载量:795
全部作者: 许啸虎,吴笑,肖凤英,郑翠红
作者单位: 华中科技大学同济医学院附属同济医院中西医结合研究所;武汉市中医医院内分泌科
摘 要: 目的:观察疏肝理脾方药配合胰岛素治疗2型糖尿病伴高脂血症疾病的临床疗效。方法:设治疗组30例,对照组30例。两组均给予一般治疗加标准胰岛素降糖治疗。治疗组加服疏肝理脾中药汤剂治疗,对照组则不采用中药汤剂治疗,疗程均为8周。患者按治疗前,治疗第2,4,8周共4个时间分别测定糖化血红蛋白(glycated hemoglobin,HbA1C)、甘油三酯(triglycerides,TG)、总胆固醇(total cholesterol,TC)、高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-c)、低密度脂蛋白胆固醇(low density lipoprotein cholesterol,LDL-c),同时观察体重变化及临床症状。结果:治疗2周后两组TG均有改善,但两组间比较无统计学差异。治疗4周后,治疗组在升高HDL-c及降低TC,TG,维持HbA1C稳定等方面明显优于对照组(P<0.05)。治疗组临床症状较对照组有明显好转(P<0.05)。治疗 8 周后,治疗组在升高 HDL-c 及降低 TC,TG,维持 HbA1C稳定等方面明显优于对照组(P<0.05)。此外,治疗组在改善患者临床症状方面明显优于对照组(P<0.05)。结论:疏肝理脾法配合胰岛素治疗 2 型糖尿病伴高脂血症在改善患者临床症状及提高临床疗效等方面均优于一般单纯胰岛素治疗。
关 键 词: 中西医结合医学;疏肝理脾法;2型糖尿病;高脂血症;临床观察
Title: Thirty cases of clinical observation of liver dispersing with spleen strengthening combined with insulin to treat type 2 diabetes with hyperlipidemia
Author: XU Xiaohu, WU Xiao, XIAO Fengying, ZHENG Cuihong
Organization: Institute of Integrated Traditional Chinese and Western Medicine, Tongji Affiliated Hospital, Tongji Medical College, Huazhong University of Science and Technology; Department of Endocrinology, Wuhan Hospital of Traditional Chinese Medicine
Abstract: Objective: To observe the influence of the therapy of liver dispersing with spleen strengthening combined with insulin on type 2 diabetes with hyperlipidemia. Methods: Sixty patients were divided into treatment group and control group, each group was 30. All patients were given general treatment and standard insulin hypoglycemic therapy during the treatment. The treatment group took decoction of liver dispersing with spleen strengthening while the control group did not. The courses of treatment are 8 weeks. Glycated hemoglobin (HbA1C), triglycerides (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-c) and low density lipoprotein cholesterol (LDL-c) were measured at the baseline and 2, 4, 8 weeks after randomization while the body-weight changes and clinical symptoms were observed. Results: TG were improved after 2 weeks of treatment in each group, but there was no significant difference between the two groups. HDL-c were increased and TC, TG, HbA1C were better improved after 4 weeks' treatment compared with the control group (P<0.05). HDL-c were increased and TC, TG, HbA1C were better improved after 8 weeksʼ treatment compared with the control group (P<0.05). The clinical symptoms were improved in treatment group compared with the control group after intervention (P<0.05). Conclusion: The therapy of liver dispersing with spleen strengthening combined with insulin were better than ordinary insulin therapy alone in improving clinical symptoms and clinical efficacy in the treatment of type 2 diabetes with hyperlipidemia.
Key words: integrated traditional Chinese and western medicine; liver dispersing with spleen strengthening; type 2 diabetes; hyperlipidemia; clinical observation
发表期数: 2015年9月第17期
引用格式: 许啸虎,吴笑,肖凤英,等. 疏肝理脾法配合胰岛素治疗2型糖尿病伴高脂血症30例临床疗效观察[J]. 中国科技论文在线精品论文,2015,8(17):1818-1823.
 
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