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高效液相色谱钛胶整体柱的制备及其应用

发表时间:2016-12-15  浏览量:1723  下载量:766
全部作者: 丁夏利,董钰明
作者单位: 兰州大学药学院,药物分析研究所
摘 要: 与硅胶基质整体柱相比,钛胶整体固定相具有更高的选择性、特异性和酸碱稳定性,尤其对带有磷酸基团的生物样品的分离富集方面已表现出很好的应用价值。本文综述了钛胶整体柱的制备方法及其在高效液相色谱(high performance liquid chromatography,HPLC)分析中的应用研究,对其制备过程提出几点建议并展望了该领域的发展前景。
关 键 词: 药物分析;高效液相色谱;钛胶整体柱;制备方法;应用进展
Title: Preparation and application of high performance liquid chromatography titanium gel monolithic column
Author: DING Xiali, DONG Yuming
Organization: Institute of Pharmaceutical Analysis, School of Pharmacy, Lanzhou University
Abstract: Compared with silica-based monolithic column, titanium gel monolithic stationary phase has higher selectivity, specificity and pH stability, especially with regard to the separation and enrichment of biological samples of phosphate groups, and it has shown a good application value. Advances in preparation of titanium gel monolithic columns and their applications in high performance liquid chromatography (HPLC) are reviewed in this paper in order to draw attention and development prospect in the field of their manufacturing process.
Key words: pharmaceutical analysis; high performance liquid chromatography; review; titanium gel monolithic column; preparation method; application progress
发表期数: 2016年12月第23期
引用格式: 丁夏利,董钰明. 高效液相色谱钛胶整体柱的制备及其应用[J]. 中国科技论文在线精品论文,2016,9(23):2403-2410.
 
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