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慢性膝关节疼痛针刺治疗的表型组学再分析

发表时间:2017-08-15  浏览量:96  下载量:27
全部作者: 刘承宜,杨罗丹,吴冲云,朱玲,段锐,张全光
作者单位: 华南师范大学体育科学学院激光运动医学实验室;美国佐治亚摄政王大学佐治亚医学院分子医学与遗传学研究所
摘 要: 毫针或激光针刺治疗50岁以上患者的慢性膝关节疼痛的效果并不优于激光假照射。研究引入定量差异(quantitative difference,QD)、自相似和拓扑空间进行表型组学再分析。研究发现,在12周治疗阶段,毫针与激光假照射疗效相当,均优于激光组;停止治疗阶段,毫针疗效保持,但激光或激光假照射疗效不再;一年内,毫针和激光治疗建立了各对参数的自限性过程,激光假照射建立了除包含活动限制的参数对之外的各对参数的自限性过程。结果表明,毫针、激光和激光假照射对50岁以上膝关节疼痛患者的治疗效果由高到低依次优于对照组。
关 键 词: 体育科学其他学科;疼痛;骨关节炎;针刺;激光;表型组学
Title: Phenomics reanalysis on therapeutic effects of acupuncture on chronic knee pain
Author: LIU Chengyi, YANG Luodan, WU Chongyun, ZHU Ling, DUAN Rui, ZHANG Quanguang
Organization: Laboratory of Laser Sports Medicine, College of Physical Education and Sports Science, South China Normal University;Institute of Molecular Medicine and Genetics, Medical College of Georgia at Georgia Regents University
Abstract: Neither needle nor laser acupuncture is superior in performance to sham laser for pain or function in patients older than 50 years with moderate or severe chronic knee pain. This paper introduced the quantitative difference (QD), self-similarity and topological space in terms of phenomics reanalysis. It was found that the therapeutic effects of needle group was similar to the sham laser group, which were better than that of laser during 12 week treatment. The therapeutic effects of needle group was maintained for one year long after treatment discontinued, but that of laser group and sham laser group were not. All the parameter pairs of needle, laser group and sham laser group were self-limited during the one year observation, except for the activity restrict related parameter pairs of sham laser group. It was suggested that needle, laser and sham laser acupuncture is superior in performance of pain or function in patients older than 50 years to control group successively.
Key words: other subjects of sports science; pain; osteoarthritis; acupuncture; laser; phenomics
发表期数: 2017年8月第15期
引用格式: 刘承宜,杨罗丹,吴冲云,等. 慢性膝关节疼痛针刺治疗的表型组学再分析[J]. 中国科技论文在线精品论文,2017,10(15):1780-1785.
 
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