您的位置:首页  > 论文页面

Ddx5和Ddx17在肿瘤中的表达调控及意义

发表时间:2018-05-15  浏览量:241  下载量:46
全部作者: 郭菲菲,康岚
作者单位: 大连医科大学肿瘤干细胞研究院
摘 要: Ddx5与Ddx17同属RNA解旋酶DEAD-box家族成员,参与从RNA形成到降解的所有过程,在结构与功能上有90%以上的相似性。但在某些功能和肿瘤疾病等方面也存在很大的不同。本文将从来源、亚细胞定位、结构与功能等方面阐述Ddx5与Ddx17在肿瘤中的表达调控及其对疾病治疗的意义,旨在成为药物研发的靶标,以期达到治疗疾病的目的。
关 键 词: 分子生物学;肿瘤;综述;Ddx5;Ddx17
Title: Expression regulation and significance of Ddx5 and Ddx17 in tumors
Author: GUO Feifei, KANG Lan
Organization: Institute of Cancer Stem Cell, Dalian Medical University
Abstract: Ddx5 and Ddx17 are the members of DEAD-box family in RNA helicase. They are involved in the process from the form to degradation of RNA. And they have more than 90% similarity in structure and function. However, there exist signifrcant differences in some functions and cancers. Thus, we elaborate the expression regulation of tumors and the significance of disease treated of Ddx5 and Ddx17 in sources, subcellular localization, structure and functions. It is expected to be the target in drug development, in order to achieve the purpose of treating diseases.
Key words: molecular biology; tumors; review; Ddx5; Ddx17
发表期数: 2018年5月第9期
引用格式: 郭菲菲,康岚. Ddx5和Ddx17在肿瘤中的表达调控及意义 [J]. 中国科技论文在线精品论文,2018,11(9):862-870.
 
3 评论数 0
暂无评论
友情链接