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Spike蛋白的生物信息学研究分析

发表时间:2022-09-29  浏览量:308  下载量:34
全部作者: 郑柳凤,伊嘉豪,梁定发,叶远浓
作者单位: 贵州医科大学大健康学院生物信息学与生物医学大数据挖掘实验室
摘 要: 本研究通过挖掘国内外文献,系统地分析了Spike(S)蛋白的作用机制和生物信息学方面的研究进展。总结目前国内外科学家利用生物信息学领域工具开发Spike蛋白的药物、疫苗等方面的研究。此外,还对现有的Spike蛋白数据资源进行了系统整理。总结分析了现有国内外与Spike蛋白相关的生物信息学工具及数据库,最后对病毒Spike蛋白在该领域的研究提出了展望。本综述旨在为研究Spike蛋白的生物学家、病毒学家等研究人员提供系统的Spike蛋白研究参考,以促进Spike蛋白机制研究、有效药物和疫苗研发。
关 键 词: 生物物理学;Spike蛋白;综述;冠状病毒;SARS-CoV-2;生物信息学;数据库
Title: Analysis of bioinformatics research on Spike protein
Author: ZHENG Liufeng, YI Jiahao, LIANG Dingfa, YE Yuannong
Organization: ical Big data Mining Laboratory, Department of Medical informatics, School of Big Health, Guizhou Medical University, Guiyang, Guizhou 550025, China
Abstract: This study systematically analyses the mechanism of Spike(S) protein and bioinformatics research progress by mining domestic and foreign literatures. This paper summarizes the current research on use of bioinformatics tools by scientists at home and abroad to develop drugs and vaccines research of Spike protein. In addition, the existing Spike protein data resources are systematically organized. Related bioinformatics tools and databases are summarized, and the research prospects of Spike protein in this field are proposed. This review aims to provide systematic Spike protein research references for biologists, virologists and other researchers who study Spike proteins. It promotes the research of Spike protein mechanism and the development of effective drugs and vaccines.
Key words: biophysics; Spike protein; review; coronavirus; SARS-CoV-2; bioinformatics; database
发表期数: 2022年9月第3期
引用格式: 郑柳凤,伊嘉豪,梁定发,等. Spike蛋白的生物信息学研究分析[J]. 中国科技论文在线精品论文,2022,15(3):288-294.
 
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